Questions? CONTACT US +1 (707) 451-6060

Biopharmaceutical Industry

With almost 25 years of experience, Synder Filtration has proven to be one of the top suppliers of membrane filtration technology throughout the biopharmaceutical industry. As a manufacturer of both membranes and systems, we strive to provide quality products and reliable service for our customers around the world. Our ultrafiltration line of elements has gradually expanded over the years, to contain one of the most extensive pore size ranges available for use in applications such as enzyme concentration and endotoxins removal. Our nanofiltration line of elements has also proven effectiveness for applications such as antibiotics production and protein desalination and concentration. For these reasons, we take pride in fully understanding the needs of our customers in order to produce membranes and systems suitable for their separation needs.


Antibiotics Production

There are few products where quality and consistency are as important to human health as in the production of antibiotics. Synder Filtration’s NFX Nanofiltration membrane can be used to obtain the purity and consistency demanded by consumers their regulatory bodies. 

Blood Protein Concentration

Blood Serum is blood plasma without the compound fibrinogen or other clotting compounds. Once the serum and plasma have been separated, Synder’s NFX membrane is capable of capturing fibrinogen and other clotting compounds. 

Endotoxin & Pyrogen Removal

Removal of harmful substances is a key step in quality control during the production of pharmaceutical products. While Microfiltration can remove microbes and bacteria, endotoxins and pyrogens are removed by Synder Filtration’s Ultrafiltration membranes. Different UF membranes are capable of capturing and removing endotoxins and pyrogens based on their molecular weight. Contact us to find out which product is right for your unique application. 

Enzyme Concentration

Synder is a leading supplier of Ultrafiltration membranes and systems to the Enzyme industry worldwide. Synder MT & ST membranes are widely accepted as the standard for enzyme concentration, and FR & V0.1 membranes are commonly used for later-stage clarification and removal of residual cell bodies, although prior filtration by Diatomacious Earth is typically required. 

Polypeptide Concentration

Synder’s wide range of Ultrafiltration membranes provide the ideal method for concentrating polypeptides for production. UF membranes can be used to not only concentrate but purify polypeptides while providing outstanding quality and consistency.


Synder offers a wide range of Microfiltration, Ultrafiltration and Nanofiltration membranes suitable for various biopharmaceutical applications.

Membrane filtration technology has played a major role in recovering and purifying the antibiotics from enzyme-based fermentation broth, including lactames, aminoglycosides, polypeptides, tetracyclines, and macrolides. The molecular mass (MW) of antibiotics are in the range of 200-1200 Daltons, therefore, nanofiltration membrane falls in the right MWCO range to concentrate and purify the antibiotics. Common membranes used for this type of application include NFXNFWNFG.

Membrane filters can also be used to extract protein concentrates from animal blood, for use as exceptional emulsifiers. Proper treatment for the blood is important, as serious pollution problems can ensue if BOD levels in the wastewater from slaughterhouses get too high.

In addition, Ultrafiltration membranes have the ability to concentrate protein solutions and recover enzymes. Due to the heat-sensitive property of active enzymes, membrane filtration is more preferable to concentrate the substance as oppose to other conventional techniques such as vacuum evaporation. This filtration method has proven to be a cost-effective way to concentrate and purify the proteins and enzymes, with dry methods integrated in later stages if necessary.

Case Study

The rise in antibiotic consumption lends forth the need for new technology to remove it from wastewater and prevent further contamination in aquatic environments. The presence of antibiotics in aquatic environments is leading to adverse health effects for both animals and humans, and the removal of antibiotics is important for the reuse of wastewater. Certain strains of disease-causing bacteria are also beginning to develop resistance large doses of antibiotics. Given that the size of most antibiotics falls within the range of 200 to 1,200 Daltons, nanofiltration membranes have the potential to be widely successful for antibiotics removal in wastewater treatment.



Synder also offers a comprehensive application development program including feasibility testing for newer specialty process applications. Please contact us for more information. You will receive a personal response from one of our experienced team members within 24 hours

Application Development Program

Learn more about Synder’s comprehensive custom application development program and wide variety of pilot systems available for testing. Here at Synder, we realize the importance of flexibility and responsiveness, which is why we created a comprehensive application development program to fulfill specific separation needs. We work closely with our customers to fully understand, design, and deliver both custom membranes and systems.

questions? Fill out this form. We’ll contact you within 24 hours!

At Synder Filtration, we take pride in providing technical expertise and personal collaboration with our customers. With our newly designed research & development laboratory and fleet of pilot systems, we are able to conduct a wide range of feasibility tests both in-house and on-site. … [read more]

Membrane Development Program
At Synder Filtration, we aim to provide quality products, technical expertise, and quick responsiveness. With our state-of-the-art laboratory, extensive array of pilot systems, and growing team of scientists and engineers, we are able to develop and customize innovative membranes to fit specific process separation needs and applications across all industries. We take pride in collaborating closely with our customers to ensure consistent… [read more]

Contact Us