Polypeptide ConcentrationWith improvements in product technology and the expansion of amino acid usage, membrane filtration has been evaluated for its ability to achieve separation of proteins and peptides from amino acids. Other than extraction, ion-exchange, evaporation, and distillation, it was found membrane filtration is a simple procedure that can extract and purify amino acid from fermentation broth via step-by-step filtration. As the first step, microfiltration is used to remove high levels of suspended solids found in the broth. The consistent permeate quality from the microfiltration process makes the downstream process easier. After microfiltration is employed, ultrafiltration is utilized to purify amino acids from proteins. The UF permeate is then processed viananofiltration to concentrate and desalinate the amino acids.
Benefits of membrane process
- Simplicity and ease in separation methods
- High recovery and minimal waste
FR, V0.1; NFX, NFW; XT
Application Development Program
Learn more about Synder’s comprehensive custom application development program and wide variety of pilot systems available for testing. Here at Synder, we realize the importance of flexibility and responsiveness, which is why we created a comprehensive application development program to fulfill specific separation needs. We work closely with our customers to fully understand, design, and deliver both custom membranes and systems.
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At Synder Filtration, we take pride in providing technical expertise and personal collaboration with our customers. With our newly designed research & development laboratory and fleet of pilot systems, we are able to conduct a wide range of feasibility tests both in-house and on-site. … [read more]
Membrane Development ProgramAt Synder Filtration, we aim to provide quality products, technical expertise, and quick responsiveness. With our state-of-the-art laboratory, extensive array of pilot systems, and growing team of scientists and engineers, we are able to develop and customize innovative membranes to fit specific process separation needs and applications across all industries. We take pride in collaborating closely with our customers to ensure consistent… [read more]