Biopharmaceutical Industry


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Cell Broth Clarification

The fermentation broth produced from different microbial sources (fungal, yeast, or bacteria) has to be harvested prior to the recovery of target molecules such as proteins and enzymes from cultivation media. Compared to centrifugation techniques which can be costly and challenging, crossflow microfiltration technology can be used as a cost-effective alternative to clarify the fermentation broth without changing the nature and activity of the target molecules. Among the different target molecules, some famous examples include penicillin and lactic acid recovery from fermentation broth via microfiltration.

Synder offers flat sheet membrane and spiral wound elements in 2”, 4”, 6” and 8” diameters with a selection of different feed channel spacers to match your clarification needs.

Benefits of membrane process

  1. Cost-effective method for broth clarification
  2. Improve process efficiency and simplify separation requirements

Recommended membrane:

FR & V0.1

Application Development Program

Learn more about Synder’s comprehensive custom application development program and wide variety of pilot systems available for testing. Here at Synder, we realize the importance of flexibility and responsiveness, which is why we created a comprehensive application development program to fulfill specific separation needs. We work closely with our customers to fully understand, design, and deliver both custom membranes and systems.

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At Synder Filtration, we take pride in providing technical expertise and personal collaboration with our customers. With our newly designed research & development laboratory and fleet of pilot systems, we are able to conduct a wide range of feasibility tests both in-house and on-site. … [read more]

Membrane Development Program
At Synder Filtration, we aim to provide quality products, technical expertise, and quick responsiveness. With our state-of-the-art laboratory, extensive array of pilot systems, and growing team of scientists and engineers, we are able to develop and customize innovative membranes to fit specific process separation needs and applications across all industries. We take pride in collaborating closely with our customers to ensure consistent… [read more]

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