There are few products where quality and consistency are as important to human health as in the production of antibiotics. Synder Filtration’s NFX Nanofiltration membrane can be used to obtain the purity and consistency demanded by consumers their regulatory bodies.
Blood Serum is blood plasma without the compound fibrinogen or other clotting compounds. Once the serum and plasma have been separated, Synder’s NFX membrane is capable of capturing fibrinogen and other clotting compounds.
Removal of harmful substances is a key step in quality control during the production of pharmaceutical products. While Microfiltration can remove microbes and bacteria, endotoxins and pyrogens are removed by Synder Filtration’s Ultrafiltration membranes. Different UF membranes are capable of capturing and removing endotoxins and pyrogens based on their molecular weight. Contact us to find out which product is right for your unique application.
Synder is a leading supplier of Ultrafiltration membranes and systems to the Enzyme industry worldwide. Synder MT & ST membranes are widely accepted as the standard for enzyme concentration, and FR & V0.1 membranes are commonly used for later-stage clarification and removal of residual cell bodies, although prior filtration by Diatomacious Earth is typically required.
Synder’s wide range of Ultrafiltration membranes provide the ideal method for concentrating polypeptides for production. UF membranes can be used to not only concentrate but purify polypeptides while providing outstanding quality and consistency.
Synder offers a wide range of Microfiltration, Ultrafiltration and Nanofiltration membranes suitable for various biopharmaceutical applications.
Membrane filtration technology has played a major role in recovering and purifying the antibiotics from enzyme-based fermentation broth, including lactames, aminoglycosides, polypeptides, tetracyclines, and macrolides. The molecular mass (MW) of antibiotics are in the range of 200-1200 Daltons, therefore, nanofiltration membrane falls in the right MWCO range to concentrate and purify the antibiotics. Common membranes used for this type of application include NFX, NFW, NFG.
Membrane filters can also be used to extract protein concentrates from animal blood, for use as exceptional emulsifiers. Proper treatment for the blood is important, as serious pollution problems can ensue if BOD levels in the wastewater from slaughterhouses get too high.
In addition, Ultrafiltration membranes have the ability to concentrate protein solutions and recover enzymes. Due to the heat-sensitive property of active enzymes, membrane filtration is more preferable to concentrate the substance as oppose to other conventional techniques such as vacuum evaporation. This filtration method has proven to be a cost-effective way to concentrate and purify the proteins and enzymes, with dry methods integrated in later stages if necessary.
The rise in antibiotic consumption lends forth the need for new technology to remove it from wastewater and prevent further contamination in aquatic environments. The presence of antibiotics in aquatic environments is leading to adverse health effects for both animals and humans, and the removal of antibiotics is important for the reuse of wastewater. Certain strains of disease-causing bacteria are also beginning to develop resistance large doses of antibiotics. Given that the size of most antibiotics falls within the range of 200 to 1,200 Daltons, nanofiltration membranes have the potential to be widely successful for antibiotics removal in wastewater treatment.
Amoxicillin Removal via NF
NFX (TFC 150-300Da) Sanitary Specsheet
NFW (TFC 300-500Da) Sanitary Specsheet
NFG (TFC 600-800Da) Sanitary Specsheet
XT (PES 1kDa) Sanitary Specsheet
MT (PES 5kDa) Sanitary Specsheet
ST (PES 10kDa) Sanitary Specsheet
FR (PVDF 800kDa) Sanitary Specsheet
V0.1 (PVDF 0.1um) Sanitary Specsheet
Synder also offers a comprehensive application development program including feasibility testing for newer specialty process applications. Please contact us for more information. You will receive a personal response from one of our experienced team members within 24 hours